Sunday, May 27, 2012

Chevrolet Volt vs. Nissan Leaf



The plug-in hybrid 2011 Chevrolet Volt and the all-electric 2011 Nissan Leaf both arrive in dealer showrooms in fall 2010.  Both have been making headlines for months.  Will they both be winners or will one leave the other in the dust?

Let’s compare the two.

Price to buy –  Both vehicles quality for a $7,500 tax rebate

Nissan Leaf — $32,780

Chevrolet Volt – $41,000

Leasing cost –

Nissan Leaf – $349 a month for 36 months, with $2,000 down

Chevrolet Volt – $350 a month for 36 months, with $2,500 down

Leasing avoids sticker shock, and also avoids owning if the technology does not live up to its promise by the time the lease is up.  Notice, I am not using the word ‘lemon’.

Size –

Nissan Leaf – four passenger compact

Chevrolet Volt – four passenger mid-size.  According to the New York Times, the Volt has less head and leg room than the $17,000 Chevrolet Cruze

Fuel mileage and range –

Nissan Volt — has a range of just under 100 miles before it needs recharging

Chevrolet Volt — also can travel about 40 miles on pure electric power, but extended range gas engine provides up to 500 miles.  The Volt requires premium gas, which detracts from fuel savings,

Recharging –  Both vehicles can be charged overnight on a standard 120-volt outlet, in four to six hours on a heavy duty 240-volt

View the original article here

Honda Planning a Major Jump in Hybrid Sales in Japan in 2011


Honda will put pedal to the metal in Japan next year when a new and bigger range of hybrid models will land on the market.


Joining the CR-Z and Fit Hybrid on the scene will be a hybridized version of the Freed, Honda’s quirky small domestic van. Honda will also introduce a stretched wagon version of the Fit hybrid for domestic consumption, according to sources. The front half of the body will be stock, but overall length will stretch by more than 2 feet.


The Fit hybrid wagon is expected out in March, while the Freed hybrid will arrive later, around fall 2011.


The redesigned Civic Hybrid, to be unveiled in January at the 2011 Detroit Auto Show and tipped to be the first Honda hybrid to get a lithium-ion battery pack, will be another 2011 debut, but Japan, in fact, might not get it.


Having announced the end of Civic sales in Japan and with that longer Fit hybrid wagon in the wings, Honda may feel that it doesn’t need the new Civic Hybrid in Japan anymore, not even as an iconic stand-alone model.


Honda will also have the Insight to fall back on, of course, and the good news there is that that to-date lackluster model is due for a major revamp next July.


Toyota will counter with a hybrid version of the new Vitz (Yaris) and Mazda is promising a face-lifted Mazda 2 with the automaker’s new Skyactiv G gas engine that can achieve hybrid-type economy without the weight and complexity of battery and motor.


Add it up and, although the technology is light and compact, Honda’s IMA hybrids have yet to truly catch on and/or frighten Toyota, the market leader. So will 2011 at last be the turning point for Honda?


Inside Line says: The new Honda hybrids could be big in Japan where the word “hybrid” is a major come-on, but in the U.S., given the inevitable price premium for the technology, such small gasoline-electric models could be a harder sell.


SOURCE: InsideLine.com


View the original article here

Honda Planning a Major Jump in Hybrid Sales in Japan in 2011


Honda will put pedal to the metal in Japan next year when a new and bigger range of hybrid models will land on the market.


Joining the CR-Z and Fit Hybrid on the scene will be a hybridized version of the Freed, Honda’s quirky small domestic van. Honda will also introduce a stretched wagon version of the Fit hybrid for domestic consumption, according to sources. The front half of the body will be stock, but overall length will stretch by more than 2 feet.


The Fit hybrid wagon is expected out in March, while the Freed hybrid will arrive later, around fall 2011.


The redesigned Civic Hybrid, to be unveiled in January at the 2011 Detroit Auto Show and tipped to be the first Honda hybrid to get a lithium-ion battery pack, will be another 2011 debut, but Japan, in fact, might not get it.


Having announced the end of Civic sales in Japan and with that longer Fit hybrid wagon in the wings, Honda may feel that it doesn’t need the new Civic Hybrid in Japan anymore, not even as an iconic stand-alone model.


Honda will also have the Insight to fall back on, of course, and the good news there is that that to-date lackluster model is due for a major revamp next July.


Toyota will counter with a hybrid version of the new Vitz (Yaris) and Mazda is promising a face-lifted Mazda 2 with the automaker’s new Skyactiv G gas engine that can achieve hybrid-type economy without the weight and complexity of battery and motor.


Add it up and, although the technology is light and compact, Honda’s IMA hybrids have yet to truly catch on and/or frighten Toyota, the market leader. So will 2011 at last be the turning point for Honda?


Inside Line says: The new Honda hybrids could be big in Japan where the word “hybrid” is a major come-on, but in the U.S., given the inevitable price premium for the technology, such small gasoline-electric models could be a harder sell.


SOURCE: InsideLine.com


View the original article here

Saturday, May 26, 2012

Honda to Start Testing EVs, PHEVs in Japan


Honda Motor Co Ltd announced Dec 20, 2010, that it will start field tests of its electric vehicle (EV) and plug-in hybrid electric vehicle (PHEV) in Japan.


On the same day, the company showed prototypes of an EV based on the Fit minicar and a PHEV based on the Inspire sedan.


Honda announced a prototype of the EV and the platform of the PHEV at the Los Angeles Motor Show, which took place in November 2010. And the vehicles announced this time were their new versions designed for the Japanese market.


“For expanding the use of EVs, the balance between price and performance is important,” Honda President Takanobu Ito said. “It is still difficult to achieve the balance. But there may be markets in specific regions such as rural areas where there is no service station.”


Honda will conduct the field tests in Saitama and Kumamoto prefectures in Japan. For each field test, five EVs and five PHEVs will be used. And the company will conduct similar field tests in Torrance, the US, by using three EVs and three PHEVs.


It is also planning to conduct field tests in Stamford, the US, by using the “EV-neo” electric two-wheeled vehicle and the “Monpal ML200? electric cart in addition to EVs and PHEVs.


“Though we have not determined a specific period of time for the tests, it will be about two years,” the company said.


In Saitama Prefecture, the vehicles will be tested in various areas depending on their characteristics. For example, in Saitama City, Honda will examine how the EV and the electric two-wheeled vehicle can be selectively used in the areas around train stations.


In Kumagaya City, Honda will test the “Park & Ride” system, which combines EVs, PHEVs and trains in the area around the Kagohara Station. In Chichibu City, the company will establish a system by using the Monpal.


This time, Honda also disclosed a charging station equipped with photovoltaic batteries developed by Honda Soltec Co Ltd. The station has a rapid charger manufactured by Kyuki Corp, a subsidiary of Kyushu Electric Power Co Inc, and three normal chargers manufactured by Nihon Unisys Ltd.


“Supposing that an EV travels 40km per day, we would like to supply electricity to four EVs by using only solar batteries,” Ito said.


As for charging technologies, Honda developed a system to monitor the use of chargers, etc in real time by using car navigation systems and smartphones. The system utilizes the company’s “Internavi Premium Club” telematics service, which uses a dedicated communication device equipped in the Fit.


Moreover, Honda mounted another communication device on vehicles to collect data on the use of automotive batteries.


SOURCE: TechOn


View the original article here

Sunday, May 13, 2012

How to cope with a family member with mental illness


Many families face a situation of dealing with a mental illness, but are not sure how to handle the situation. Understanding how to cope with a family member who has mental illness is not something that many people discuss openly. However, knowing how you can manage through what may seem like a painful situation can bring comfort to many families. 


Depending on the type and severity of mental illness, typical communication methods may not work. This can be one of the trickier aspects when learning how to cope with a family member who has mental illness. For some, reasoning and common sense are lowered, which can make communication much slower. Others may become easily agitated or upset, forcing families to choose their words carefully. 


If your attempts at communicating have not worked, seeking help from a professional is an important part of learning to cope with a family member who has mental illness. Professionals can help teach you ways to communicate that will not create frustration or anger in either party, and may bring about a sense of bonding. 


For many with mental illnesses, it can be frustrating to be expected to do things that are extremely difficult, or even impossible. Learning new skills, communicating, and processing information may be harder to do. Those who are learning how to cope with a family member with mental illness need to practice patience and sensitivity. 


Some people with mental illnesses can be treated with medications, and while these may reduce or prevent some of the problems they do not necessarily erase the mental illness completely. Patience and sensitivity are still very important even if your family member is receiving treatment and seems to be better. Things on the outside do not always reflect how things feel on the inside, this is an important lesson for those who are learning how to cope with a family member with mental illness. 


Different mental illnesses can affect people in different ways. In learning how to cope with a family member who has mental illness, making an effort to understand the particular mental illness is very important. The more yo understand, the easier it may be to cope with problems that arise. If you are prepared you can expect common complications, and know what to look for in case things become worse. 


It can be very hard to see a person change in personality, behavior, and ability due to a mental illness. In times past, those with mental illnesses were treated as less than humans and often abused. For some with severe cases of mental illness, it may seem very difficult to see the human still inside the body. 


Yet, it is crucially important to remember that this person is still the same family member you knew and loved. A mental illness does not destroy the basic needs of a human: to be loved and cared for. 



View the original article here

How to Choose a Family Doctor


Of the many ways that a family can stay healthy, choosing a family doctor is one of the most important. Finding a doctor that your family can trust, feel comfortable with, and develop a long-term relationship with can be crucial to maintaining family health. If you are looking for a new doctor to provide health care for your family, here are some ways that you can make the right decision for you.
Before you go in for the first visit, take time to decide what it is that you want. Choosing a family doctor can be a different experience for each family, simply because each family has their own expectations. As a family, sit down and discuss what it is that your family wants and needs with your health care.
Some families may prefer a doctor that offers more natural based medicine, while other families may feel more comfortable with modern interventions during care. Some doctors spend time discussing issues with their patients, while others prefer efficiency and getting things done. Knowing what your family needs before hand makes choosing a family doctor easier over all.
Before setting up an appointment, you can review the doctors in your area to make sure they will be good fit. Check with your insurance company to see which doctors are on your list as allowed. Some doctors may not be covered under your insurance policy, or may only be partially covered. If money is a concern, you will want to look at how much your insurance will cover when choosing a family doctor.
You can look to other people's recommendations when choosing a family doctor. Friends and family members can often give their experiences with family doctors that they have used. You can also review them on websites such as Healthgrades.com, an online review site dedicated to doctors and hospitals. These can give you a better understanding of which doctors you may want to consider.
Before dropping your family into a new doctor's lap, call and arrange trial visits to discuss your family's needs and concerns. You may need to visit several doctors, and these visits may not be covered by your insurance company. However, meeting with a doctor face to face can give you a better idea of their personality and medical disposition.
Families with unique medical needs may need to travel outside of their immediate area to find the right family doctor for them. Do not be afraid to search in nearby towns and cities when choosing a family doctor. Families that live in rural areas may find they need to travel longer distances to find the right doctor for them.
Choosing a family doctor is an important part of maintaining your family's health and well-being. Take your time to find a doctor that will fit with what your family needs. Some may find it takes a lot of trial and error to find the right doctor, but having something that you can trust with your family's care is worth the effort.

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How to Help Your Family Lose Weight


More and more people are facing obesity today, and some experts believe it is a family concern. If you are worried about how to help your family lose weight, you may be happy to know that the weight gain trend can be reversed. A family weight loss plan is a simple way to help your family lose weight together.


The family that eats together can either gain or lose weight together. Let healthy eating become a family event by encouraging everyone to eat better. Involve the entire family in grocery shopping and meal planning, let them choose the foods they want to eat. You may need to spend time talking with children the differences between healthy foods and unhealthy foods. Encourage them to choose fruits and vegetables over candy or fast food.


When cooking meals, use healthier cooking methods. Frying foods can strip nutrients, and usually uses large amount of oil. To help your family lose weight, make a change to baking and steaming foods instead. Some vegetables can even be served raw as side dishes. This maintains their full nutritional value and can be much healthier to eat.


Exercise can be a fun family activity. When looking for ways to help your family lose weight, consider fun activities that the entire family can take part in. Family walks, swimming, and even joining in a sport together can all be fun ways to lose weight. At least three days each week, make a point of do a family activity together. You can help your family lose weight, and enjoy the fun bonding that these things can bring.


There are also many gyms that allow families to join and workout together. Parents with older children and teenagers may want to join one of these gyms in order to help the entire family lose weight. If a gym membership is too expensive, you may be able to find quality gym equipment for your home at garage sales or thrift shops. Of course, you do not have to spend money to help your family lose weight.


Families can continue their weight loss journey while on vacation. A family vacation centered around an activity or adventure can be both fun and healthy. Choose activities such as hiking, skiing, or swimming in the ocean. Your family can lose weight and still have a fun vacation that they will remember for years.


As more and more families face obesity and the health concerns that weight gain brings, there is an increased need to look at weight loss as a family affair. If you are concerned about how to help your family lose weight, you can take huge steps forward with only a few small changes. Make healthy eating and regular exercise a priority for your entire family. And do not let vacations become a time to fall back into old habits. With a little effort, you can help your family lose weight and be healthier all over. 



View the original article here

Saturday, May 12, 2012

Bridge Story - A Tale of Two Dragon Cities

 The Front Porch and Living Room of China "If China is a house, Shanghai is the living room, and the Yangze River Delta is the front porch welcoming and showing China's best side to the visitors" ---Mr. Vibul, Thai Consulate General, Shanghai, September 2002


For first time visitors to China, one of the most stunning entry points is Shanghai. The view from the mouth of the Yangze River, which looks out over Shanghai and other cities, reveals an incredible urban and industrial panorama, clearly one of the most rapidly developing areas among all the cities of the world. I recently spoke with a group of journalists and photographers from Thailand, one of whom was writing "Shanghai, the SIM city," for a Thai marketing magazine (The Marketeer). They had already seen the panorama of the Yangze River Delta and were awed by such sighs as the "walking street" (Nanjing East Road). From an outsiders' perspective, it all looked like a marvel of integrated urban development.


The reality, however, is that there has been a great deal of competition between Shanghai and other cities. It is true that there have been efforts to coordinate and cooperate, as for example in projects trying to link transportation, human resources, and administrative services systems into one huge Delta Region. Ultimately, however, there has been a great deal of mutual exclusivity. Consider, for example, this story of two bridges.

Two of the World's Longest Bridges

Two of the world's longest bridges are situated in the Bay of Hanzhou, just a stone's throw apart. Each bridge cost more than $1 billion, started construction less than a year apart.


The Hangzhou Bay Bridge (36 km) connects Cixi, Ningbo with its deep sea port, Beilun to Jiaxing, a Zhejiang city just south of Shanghai city's administrative zone. This bridge underwent various feasibility studies for a decade before construction was finally approved and begun in September, 2003. Total investment, all from private companies in Ningbo, is estimated at more than 10 billion yuan ($1.25 billion). The bridge has to connect to Jiaxing on the northern coast of the Hangzhou Bay; the city of Shanghai would not permit it to land in that city's territory.


Beilun is a small fishing town on the easternmost edge of the southern coast of Hangzhou Bay. The presence of a deep sea lane with year-round minimum depth of 17 meters stretching along the coast of Beilun motivated the Central Government to build one of the nation's largest deep sea port here. The port is further protected from storms by the mountainous islets of Zhoushan just off the coast of Beilun. Beilun port, which has grown up since the early 1990s, has earned the nickname "Rotterdam of the East" because of its natural, storm-free deep water lanes. 14.31 billion yuan has already been invested in the Beilun port. It should be noted that in 1991, it was proposed that Beilun port be managed by the Shanghai port authority. That would have been a logical move given that Shanghai's own port and water lane - a mere 11 meters deep - can only accommodate container ships and freighters of 50,000 DWT or less. Swift and dangerous undersea currents also contribute to an inefficient port that costs the city a great deal to keep open, and even then it is often only usable during high tide.


The challenge for economic development in the region has been the expensive detour from Beilun to Southern Jiangsu and Shanghai along the coast of Hangzhou Bay. The Hangzhou Bay Bridge would have reduced that 400 km trips from Beilun to about 80 km. Although the high speed superhighway along the coast takes only slightly more than 4 hours to Shanghai, the building of the bridge will make it possible for Shanghainese to drive to Ningbo for some seafood dinner and drive home in time for the 10 o'clock evening news.


The East China Sea Bridge (31 km), situated on the eastern edge of Hangzhou Bay, links the small Shanghai town of Lucaogang with a small, uninhabited island, Da Yang Shan. Total investment on the bridge alone, exclusive of the cost of infrastructure on the island and port facilities, will be 7.11 billion yuan (nearly $900 million. A further 200 billiion RMB will be invested on Da Yang Shan to make it an international deep sea port. This bridge's approval and construction was expedited to enable it to begin a year ahead of the Hangzhou Bay Bridge with scheduled completion in 2005, three years ahead of the Hangzhou Bay Bridge.


The construction of the East China Sea Bridge remains more than two years from completion. Indeed, the port authority of Shanghai has already signed an agreement for a joint venture with the city of Yi-u, Zhejiang, approximately 120 km south of Hangzhou, just off the ear of Ningbo, for a container yard to handle 200,000 containers from that city each year. Shanghai has also reached agreement on container yard project with many other cities in its ambition to become one of the major container shipping ports of the world.


Why are the two cities a bay apart not joining each other in their bridge and deep sea port project? The situation should be understood in the context of rapid economic growth and inter-city competition. The Chinese have always described themselves as "A plate of scattered sand grains" that would never join or unite with each other. Consider some of the following tales of province and city level economic growth in today's explosive Chinese economy.

The Tale of Three Kingdoms, Modern Version

The economic miracle of the reformed, opened-up China has fueled the growth of three prominent centers of economic activity situated around Hangzhou Bay and the Yangze River Delta: Southern Jiangsu, Northern Zhejiang, and Shanghai.


Southern Jiangsu. Situated on both the north and south banks of the mighty Yanze River as it makes its way to the sea, Jiangsu has carved out a niche as a center for goods and transportation for the 350 million people who live along the river. For the last decade, Jiangsu has sought ways to deepen its river lane to accommodate larger container lines and freighters. Among the key cities of the southern part of Jiangsu province are Suzhou (GDP $25.2 million), Wuxi (GDP $19.4 million), and Nanjing (GDP $15.7 billion). (Jiangsu has had on the drawing board for many years a long bridge linking its city of Nantong to Shanghai).


Northern Zhejiang. Economic growth is also apparent in Zhejiang province, where five cities accounted for over $10 billion in GDP in 2002: Hangzhou, Ningbo, Wenzhou, Shaoxing, and Taizhou. The cities, which are often referred to as the "Five Little Dragons" of Zhejiang, are reimiscent of the aspiring Asian dragons of the late 80's.


Shanghai. Shanghai's estimated year 2002 GDP was $65.5 billion - the highest in the country and more than 80 % higher than Beijing or Guangzhou (which ranked second and third). Shanghai hosts the regional headquarters of more than 300 Fortune 500 firms, in most cases including head administrative offices and financial management centres. However, it is out of those Shanghai regional headquarters that far-flung production facilities spread from Shanghai to Southern Jiangsu and Northern Zhejiangand into the very heartland of China are managed. No wonder Shanghai is now enjoying an international reputation as a dynamic, modern city and an excellent site for foreign investment!


"The Tale of the Three Kingdoms" tells of heroes rising from everywhere like the breaking surf and waves. Modern China has more than its share of municipal heroes, if not exactly rising from everywhere then certainly playing an increasingly important economic role.


The chain of cities from Kunshan to Suzhou, Wuxi, and Nanjing on the southern bank of Yangze River has been blessed with a combination of relatively easy access to the deepest heartland of China, plentiful and high quality human resources, favorable treatment by local governments, and proximity to Shanghai. Foreign investors have taken note, as in the case of Kunshan, a city under the Suzhou city administration, which appears to have one of the highest concentration of Taiwanese factories and firms.


Zhejiang Province. Another rising hero is Zhejiang province, which has a disproportionate number of businesspeople and entrepreneurs. In many cases, they are using innovative marketing strategies such as the "rurals surrounding the cities" cited in my previous Dragon column. More than half of China's leading brands of shirts, men and ladies' apparels are made in Zhejiang. Zhejiang leads all Chinese provinces in the production of motorcycles and washing machines.


Ningbo: Proud Past and Affluent Present. Many prominent and successful businessmen in Hong Kong and Shanghai trace their roots to Ningbo, a city whose 7000 years of cultural history predates the history of China itself by two millennia. Ningbo is now an economic leader, with the highest per capita volume of housing purchases in China. Ningbo's economic muscle is reflected in the way it handled its city government city redevelopment plan in 2001. In most Chinese cities, the city government buys up sufficient new housing units to give to families whose residences would have been reclaimed for the city's redevelopment plan. Ningbo, however, was forced to postpone some of its redevelopment projects because the city government had bought up so many properties there were not enough left to relocate residences in the targeted areas.


Da Yang Shan Island. Dayang Shan (The Big Ocean Mountain) and Xiaoyang Shan (The Small Ocean Mountain) are little more than two small rocks peaking above ocean level, hardly enough to be called "islands." They are located 27 km off the coast of Lucaogang town on the northern coast of Hangzhou Bay, under the administration of Shanghai city. However, Dayang Shan itself is under the administration of Zhejiang province, along with the achipelagoes at the mouth of Hangzhou Bay in East China Sea. While Shanghai's port authority had good reasons for choosing this location seven years ago when the idea of building Shanghai's own deep sea port began, problems have already surfaced. The island's sites for deep sea ports only have a depth of 15 metres, enough to accommodate only the fifth and sixth generation container liners. However, the sea lane depth of only 12 m will certainly limit access of larger ships. Unlike Beilun, which has the large Daxie Island to shield it from the wind, Dayang Shan will have to brave the weather by itself, right in the middle of the Bay of Hangzhou.


While Shanghai grabbed the containers from the throat of Beilun in Yi-u, the provincial government of Zhejiang (with strong support from wealthy Ningbo businessmen) has moved forward to build up the high speed highways linking Hangzhou with Nanjing, Wuxi and Suzhou. For these cities, Beilun port, with the new bridge much nearer and faster than the alternative of going to Dayang Shan Island via the East China Sea Bridge, represents an attractive alternative.


As the construction of the two bridges proceeds, the true color of these two little dragons will continue to be unveiled before the eyes of 1.3 billion Chinese and the international business community.


It has been noted by some astronauts that, looking down at the earth from orbit, the only significant manmade construction visible is the Great Wall of China, a massive structure that snakes along for thousands of kilometers. In the future, perhaps, the two bridges will be a new sight from outer space.


While the Great Wall was built to keep the enemies of Chinese people out of the country, in reality it never really served such a purpose for China. Socially, however, the Great Wall still segregates "insiders" from "outsiders" among Chinese. The two new bridges may be seen in much the same way. They are being constructed - in theory - to link people together and contribute to economic integration. However, it appears that are actually built to exclude certain groups and to wall off the competition, consistent with the old Chinese saying: "Let not your fertile water flow into others' land."


The key question will be whether, as projected, the two bridges and their corresponding ports will really handle over 10 million containers per year, making them among the world's busiest container sea ports. Both Shanghai and Ningbo will certainly need a lot of container transportation businesses from others' land.


Chang Hong is a housing estate built by Chinese government exclusively for foreigners in the early 1990s. However, upon completion, it was found to be below acceptable standards; the estates were then marketed and sold to Chinese residents, mostly working in the field of education and science. "Chang Hong" consists of a block approximately 300-400 meters long separating the Shanghai Teachers Training University and a big cluster of schools, a market, and kindergartens. The thousands of families of the University faculty and staff grew accustomed to sending their children to school and shopping for daily food from the market.


However, the SARS scare (April-June 2002) led to policy changes, with all of the estates locking up their north gate facing the university for most of the day in order to reduce traffic and thus the possible of spread of the dread disease. During the same period, the university locked up its gate to maintain the separation between students and faculty and outsiders. After China was given a clean bill from SARS, however, the gates of Chang Hong estate remained locked, with guards on duty and a notice denying non-residents access. This policy has caused great inconvenience for students and parents, who must make a detour of more than half a kilometer to access the school clusters and the market. The property management company of Chang Hong hired lawyers to defend its decision.


Recently, I passed through the gate of the university (as I usually do, taking advantage of my appearance that can easily be taken as a "foreign teacher"), I noticed a board written in a rather crude handwriting (apparently from some angry detour-ers):


"University village is a private property, No Chang Hong residents or their dogs are allowed to enter."


The sign disappeared after a week.


Just as I was finishing this article, on the bus, I sat in the back watching a middle age lady and her grandson board the crowded bus with its onrushing crowd trying to squeeze in ahead of one another (see ** for a description of how people virtually tackle one another on public buses). In this particular instance, the old lady was not quite quick or nimble enough, and lost out in the squeezing match for the few available seats. Instead of being irritated at the crowd or the rude people who had out-elbowed hi grandmother, the young boy shouted in protest to his grey-haired grandma: "YOU let other get ahead of you again! Why let them get ahead of you again?"


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Acomplia

          The results of a two-year Phase III study in 3040 patients with rimonabant (Acomplia), the first in a new class of therapeutic agents called selective CB1 Blockers, demonstrate that the benefits achieved with rimonabant 20mg at the end of the first year of the study were sustained in the second year of therapy with a good safety and tolerability profile versus placebo.


Patients treated with twenty milligrams of rimonabant for two years experienced a reduction in body weight and in waist circumference, demonstrating a significant reduction in abdominal fat, a key marker for cardiovascular disease. Patients treated over the two year period also achieved a significant increase in HDL-cholesterol (good cholesterol), a reduction in triglycerides and an improvement in insulin sensitivity. The RIO-North America study is the largest of all rimonabant studies presented to date. The results from this study data are consistent with the findings from two previous large-scale studies on rimonabant. Acomplia is currently being developed for the management of cardiovascular risk factors including reduction of abdominal obesity, improving lipid and glucose metabolism, and as an aid to smoking cessation.


Obesity is a major public health burden and one of the most frequent causes of death worldwide mainly through cardiovascular disease. Obesity is typically measured by body mass index (BMI). However, recent findings have shown that visceral (abdominal) fat (simply measured by waist circumference) is a better predictor for heart attack than weight or BMI. 44% of adult Americans have a waist circumference size exceeding the at-risk level (40 inches for men and 35 inches for women). Visceral fat is associated with the cause of metabolic risk factors such as dyslipidemia or insulin resistance that may lead to diabetes, heart attack, stroke and other cardiovascular disease. Reducing abdominal fat is a recognized priority for preventing cardiovascular disease.


"As the cardiovascular risk factors associated with obesity have become more manifest, it has become increasingly apparent that current approaches are insufficient. Excess abdominal fat in particular is increasingly recognized as one of the most telling harbingers of future cardiovascular complications," said Professor Pi-Sunyer. "The two-year results of the RIO-North America trial confirm that rimonabant is an innovative and promising tool for the long-term management of weight and associated cardiovascular risk factors in abdominally obese patients," he added.


RIO-North America was a Phase III, multinational multicenter, randomized, double-blind, placebo-controlled trial comparing two fixed-dose regimens of rimonabant (5mg and 20mg once daily) to placebo for a period of two years. The study was conducted on 3,040 patients at 72 centers in the United States and Canada.


The objectives of the trial were to assess the effect of rimonabant on weight loss over a period of one year and to determine the ability of rimonabant to prevent weight regain during a second year of treatment. The study objectives also included an assessment of improvement in risk factors associated with abdominal obesity (as measured by waist circumference) such as dyslipidemia, glucose metabolism, and the metabolic syndrome, and an evaluation of the safety and tolerability of rimonabant over a period of two years.


Rimonabant 20mg proved to be safe and tolerable vs. placebo throughout the two year study period. Side effects were mainly minor and short-lived. Overall discontinuation rates for adverse events in the first year of the study were 7.2%, 9.4% and 12.8% in placebo, rimonabant 5mg and rimonabant 20mg groups. The discontinuation rates for patients randomly assigned to continue their first-year treatment for a second year were 6.7%, 8.3% and 6.0% in placebo, rimonabant 5mg and 20mg groups. No differences were noted in the three groups with regards to scores measured by the Hospital Anxiety Depression scale. In this trial and in two preceding studies, rimonabant was also shown to have no significant EKG or heart rate changes.


The EC System is a newly discovered, physiological system in the body that is believed to play a key role in the central and peripheral regulation of energy balance, glucose and lipid metabolism as well as in the control of tobacco dependence.


CB1 receptors are found in the brain as well as in peripheral tissues of the body such as adipocytes (or "fat cells") which are associated with lipid and glucose metabolism. Excessive food intake or chronic tobacco use result in an overactive EC System. This can trigger a cycle of increased eating and fat storage, or, in the case of smoking, sustained tobacco dependence.


Rimonabant is the first in a new class of drugs called cannabinoid type 1 (CB1) blockers. By selectively blocking both centrally and peripherally the CB1 receptors, rimonabant modulates the overactive EC System. The results have been seen in reducing cardiovascular risk factors through reduction in abdominal fat and a corresponding improvement in metabolic parameters that is beyond that expected through weight reduction.


The new clinical results from the study suggests that rimonabant may become an important tool in cardiovascular risk factor reduction.


View the original article here

Alzheimer Drugs

 


Professor Colin Masters, a Director of Prana Biotechnology Limited and Chairman of the Company's Scientific Advisory Board, today will present data from the extended Phase II trial of Prana's drug, PBT-1, at the 8th International Springfield/Montreal Symposium on Advances in Alzheimer's Disease.


At a session devoted to novel treatments of Alzheimer's disease, Professor Masters will report that the use of PBT-1 for 18 months markedly slowed the decline in cognitive function associated with Alzheimer's disease compared with the predicted level of decline available from the scientific literature. In addition the longer term treatment was well tolerated.


The extension study was conducted over 48 weeks following the formal trial period of the trial of 36 weeks. Nine of the original 18 patients completed the extension. Speaking from Montreal, Professor Masters stated that the outcome for patients in the extension study provided confirmatory and new evidence that MPACs such as PBT-1 may form the next generation of agents for the treatment of Alzheimer's by slowing or stopping the disease rather than just dealing with the symptoms.


Dr Sam Gandy, Director of the Farber Institute for Neurosciences at Thomas Jefferson University, Philadelphia, commented: "This PBT-1 (clioquinol) extension study reaffirms the safety and possible efficacy of this new class of drug for Alzheimer's disease. It will now be important to confirm the trend toward benefit in a larger trial with sufficient numbers of subjects to establish statistical significance.


"Overall, anti-amyloid, "plaque-busting" drugs such as PBT-1 (clioquinol) provide a powerful approach toward proof of principle regarding the relationship between amyloid and cognitive decline in Alzheimer's disease," said Dr Gandy.


The biannual Symposium on Advances in Alzheimer's Disease is organized by the Southern Illinois University (SIU) School of Medicine in Springfield, Illinois, the Department of Geriatrics at the Hopitaux Universitaires de Geneve, Switzerland, and the McGill University Faculty of Medicine in Montreal, Quebec.


Recently (March 26) Prana announced that Forbes.com had added PBT-1 to its list of "neurological drugs to watch", highlighting the most promising experimental drugs to treat diseases of the brain and nervous system.


Prana also recently announced on April 7th that a publication in the Journal of Neuroscience added further support to Prana's theory that metals in the brain, rather than proteins on their own, are responsible for the pathology of Alzheimer's Disease and that attenuating the action of these metals, with drugs like PBT-1, may hold the key to effective therapeutic intervention.


PBT-1, also called clioquinol, is an example of a Metal Protein Attenuating Compound or MPAC. It is a small molecule that binds metal ions. Due to its small size and solubility in lipid, PBT-1 is able to enter the brain from the bloodstream and bind to zinc. This action can remove the zinc already bound to amyloid beta and bind free zinc to prevent its association with amyloid beta protein.


Prana is a Melbourne-based biotechnology established in 1997 to commercialize research into Alzheimer's disease and other major age-related degenerative disorders.


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Ciclopirox

Fougera received first approval from the FDA for Ciclopirox Cream 0.77% (Rx). This product is AB rated to Loprox Cream by Medicis and is available in 15g, 30g and 90g tubes.

David Klaum stated, "After recently receiving first approval for Ciclopirox Topical Suspension USP, we are excited to add this important additional first approval and first-to-market to the Ciclopirox line of products, providing the market with another quality option for their topical needs."


As a specialty pharmaceutical manufacturer of topical steroids, antibiotics and antifungal products, as well as ophthalmics, Fougera has received more topical generic FDA approvals than any other company during the past six years. This ability to provide a continuing stream of new products benefits both health care providers seeking multi-source alternatives with the ability to reduce health care costs, and patients whose conditions warrant their application.


Fougera manufactures and distributes a wide range of multi-source topical and ophthalmic pharmaceuticals, in both prescription and over-the-counter dosage forms.


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Electronic Prescriptions

SSMC will deploy ZixCorp's PocketScript e-prescribing technology to its 48 prescribers. As with other sponsored physicians and physician practices in Massachusetts, a portion of SSMC's PocketScript implementation costs will be subsidized by the eRx Collaborative.


PocketScript will enable SSMC physicians to write and generate prescriptions directly to pharmacies through either a wireless handheld PDA or a secure website. The application includes formulary information, a reference guide, allergy checking, and patient specific dispensed lists. PocketScript provides greater legibility, improved communication for greater patient safety, lower costs, and improved office efficiency.


South Shore Medical Center is rolling out its e-prescribing initiative in phases. With 31 active users in February, the practice logged 9,115 e-prescriptions written via PocketScript -- averaging more than 325 scripts per day, including weekends.


"The convenience and efficiency of PocketScript is highly valuable," said Dr. Ed Nalband of SSMC. "Not only can I prescribe from anywhere, anytime, but I have access to the medication histories of every patient in the practice, not just mine. The system also streamlines the refill process and enables the practice to have new patients entered and ready for prescriptions immediately. A big plus is that ZixCorp is willing to spend time to ensure we have everything we need to implement the system in the easiest manner possible. I feel strongly enough about PocketScript to highly recommend it to practices."


"Our expanding user base combined with the increasing number of prescriptions written using PocketScript shows that we're on the right course. Our training and utilization teams are doing an excellent job working with physicians like those at South Shore to ease the transition from pad and pen to a more efficient digital solution," said Kirk Paul Kirkman of ZixCorp.


SSMC is a multi-specialty private practice in Massachusetts.


ZixCorp provides secure e-messaging, e-prescribing, and e-transaction applications and services.


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Portable Nebulizer

 


PARI's new electronic nebulizer, the eFlow, was cleared for market by the US FDA on May 5, 2004. eFlow is a small, silent, aerosol delivery device that takes liquid medications and generates a dense aerosol that can be inhaled into the lungs. The cordless eFlow was designed to fit the needs of respiratory patients, such as COPD, asthma and cystic fibrosis sufferers, because it significantly shortens typical nebulization times and improves medication delivery compared to current nebulizers. The gentle aerosol generation of eFlow has also demonstrated the potential to aerosolize suspensions and more fragile molecules including, peptides, proteins or liposomes either avoiding or reducing degradation.


"The eFlow represents a significant advance in aerosol delivery to the lungs. Patients with CF and other chronic lung diseases are tasked with inhaling time-consuming, nebulized medicine on a daily basis. The eFlow may improve their quality of life by providing faster, silent, portable and versatile aerosol medicine delivery. Companies developing new aerosol medicines now have the opportunity to reduce the time burden of therapy," says David E. Geller, M.D., Pediatric Pulmonologist at Nemours Children's Hospital in Orlando, Florida.


The eFlow represents the opportunity to match inhaled medicine delivery between the nebulizer and the medical formulation. This is important with new treatments being developed for inhalation. Treatment times can be significantly reduced from 10-15 minutes with traditional nebulizers to as low as 3-5 minutes depending on the formulation and fill volumes. The eFlow provides an ideal platform for these developments: rapid medicine delivery, efficiency, ideal particle sizing, low residual volume, and optimal performance matched to the inhaled formula. This is an important development for patients, clinicians, third-party payors, and healthcare regulators," says Dean Hess, Ph.D., RRT, Assistant Director Of Respiratory Care Services, Massachusetts General Hospital.


"We intend to license eFlow to interested pharmaceutical companies who want to develop a unique, optimized formula and device match," says Geoff A. Hunziker, Senior Vice-President For The PARI Aerosol Research Institute, USA. "CORUS Pharma, who recently completed a Series C Round of financing, has licensed customized eFlow products for two clinical programs including inhaled aztreonam (a monobactam antibiotic) for cystic fibrosis and inhaled lidocaine for asthma. We are currently in discussions with other pharmaceutical companies interested in eFlow," added Hunziker.


"We have been impressed by the performance and patient enthusiasm to the eFlow in our clinical trials," said A. Bruce Montgomery, M.D., CEO of Corus Pharma. "PARI has been a responsive partner and their contributions have been key to our success."


"The PARI Aerosol Research Institute offers the eFlow device and comprehensive formulation expertise to optimize eFlow to specific formulations, as we did with CORUS Pharma's aztreonam project. For aztreonam, our experienced and GMP certified pharma division contributed the CMC package including the preparation of different salts, development of various formulations and the corresponding analytical methods, and finally, the match of an optimized formulation (a lyophilized aztreonam lysinate) with a customized eFlow," says Manfred Keller, Pharm. D., Ph. D., Director Pharmaceuticals and Senior Member of the PARI Executive Board.


At the core of the eFlow is a stainless steel membrane with 4,000 laser drilled holes. Laser drilling allows flexibility to customize particle size, ensure reproducibility, and maintain a high output rate with smaller particles. The perforated membrane is vibrated at high frequencies in a resonant bending mode which yields high particle output rates.


PARI is focused on new aerosol delivery technology and pharmaceutical formulation development.


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Friday, May 11, 2012

Proxinium

Viventia Biotech has received clearance from Health Canada to initiate a Phase II study evaluating Proxinium for the treatment of patients with chemotherapy-refractory recurrent head and neck cancer.


"This clearance will allow us to expand our proposed Phase II trial for Proxinium to include Canadian patients and reflects our strategy to ultimately develop Proxinium on a global basis," said Viventia's Dr. Nick Glover.


Viventia recently announced it had been cleared by the FDA to initiate a Phase II trial of Proxinium for chemotherapy-refractory recurrent head and neck cancer.


Proxinium combines a cytotoxic protein payload with the precise tumor-targeting characteristics of a monoclonal antibody.


A single molecule of the cytotoxic protein payload, Pseudomonas exotoxin, is capable of eliminating a cancer cell. The antibody fragment of Proxinium targets EpCAM -- an antigen that is highly expressed on many epithelial cancers including head and neck cancer, ensuring that the payload is delivered directly to the tumor.


Proxinium has been designated an Orphan Drug for the treatment of head and neck cancer in the U.S. and EU. Head and neck cancer is the 9th most common cancer in North America, with approximately 55,000 new cases diagnosed annually in the U.S. alone. Head and neck cancer recurs in 60 - 70% of patients.


Viventia Biotech develops powerful and precise anti-cancer drugs.


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Bridge Story - A Tale of Two Dragon Cities

 The Front Porch and Living Room of ChinaChina business, marketing, and management "If China is a house, Shanghai is the living room, and the Yangze River Delta is the front porch welcoming and showing China's best side to the visitors" ---Mr. Vibul, Thai Consulate General, Shanghai, September 2002


For first time visitors to China, one of the most stunning entry points is Shanghai. The view from the mouth of the Yangze River, which looks out over Shanghai and other cities, reveals an incredible urban and industrial panorama, clearly one of the most rapidly developing areas among all the cities of the world. I recently spoke with a group of journalists and photographers from Thailand, one of whom was writing "Shanghai, the SIM city," for a Thai marketing magazine (The Marketeer). They had already seen the panorama of the Yangze River Delta and were awed by such sighs as the "walking street" (Nanjing East Road). From an outsiders' perspective, it all looked like a marvel of integrated urban development.


The reality, however, is that there has been a great deal of competition between Shanghai and other cities. It is true that there have been efforts to coordinate and cooperate, as for example in projects trying to link transportation, human resources, and administrative services systems into one huge Delta Region. Ultimately, however, there has been a great deal of mutual exclusivity. Consider, for example, this story of two bridges.

Two of the World's Longest Bridges

Two of the world's longest bridges are situated in the Bay of Hanzhou, just a stone's throw apart. Each bridge cost more than $1 billion, started construction less than a year apart.


The Hangzhou Bay Bridge (36 km) connects Cixi, Ningbo with its deep sea port, Beilun to Jiaxing, a Zhejiang city just south of Shanghai city's administrative zone. This bridge underwent various feasibility studies for a decade before construction was finally approved and begun in September, 2003. Total investment, all from private companies in Ningbo, is estimated at more than 10 billion yuan ($1.25 billion). The bridge has to connect to Jiaxing on the northern coast of the Hangzhou Bay; the city of Shanghai would not permit it to land in that city's territory.


Beilun is a small fishing town on the easternmost edge of the southern coast of Hangzhou Bay. The presence of a deep sea lane with year-round minimum depth of 17 meters stretching along the coast of Beilun motivated the Central Government to build one of the nation's largest deep sea port here. The port is further protected from storms by the mountainous islets of Zhoushan just off the coast of Beilun. Beilun port, which has grown up since the early 1990s, has earned the nickname "Rotterdam of the East" because of its natural, storm-free deep water lanes. 14.31 billion yuan has already been invested in the Beilun port. It should be noted that in 1991, it was proposed that Beilun port be managed by the Shanghai port authority. That would have been a logical move given that Shanghai's own port and water lane - a mere 11 meters deep - can only accommodate container ships and freighters of 50,000 DWT or less. Swift and dangerous undersea currents also contribute to an inefficient port that costs the city a great deal to keep open, and even then it is often only usable during high tide.


The challenge for economic development in the region has been the expensive detour from Beilun to Southern Jiangsu and Shanghai along the coast of Hangzhou Bay. The Hangzhou Bay Bridge would have reduced that 400 km trips from Beilun to about 80 km. Although the high speed superhighway along the coast takes only slightly more than 4 hours to Shanghai, the building of the bridge will make it possible for Shanghainese to drive to Ningbo for some seafood dinner and drive home in time for the 10 o'clock evening news.


The East China Sea Bridge (31 km), situated on the eastern edge of Hangzhou Bay, links the small Shanghai town of Lucaogang with a small, uninhabited island, Da Yang Shan. Total investment on the bridge alone, exclusive of the cost of infrastructure on the island and port facilities, will be 7.11 billion yuan (nearly $900 million. A further 200 billiion RMB will be invested on Da Yang Shan to make it an international deep sea port. This bridge's approval and construction was expedited to enable it to begin a year ahead of the Hangzhou Bay Bridge with scheduled completion in 2005, three years ahead of the Hangzhou Bay Bridge.


The construction of the East China Sea Bridge remains more than two years from completion. Indeed, the port authority of Shanghai has already signed an agreement for a joint venture with the city of Yi-u, Zhejiang, approximately 120 km south of Hangzhou, just off the ear of Ningbo, for a container yard to handle 200,000 containers from that city each year. Shanghai has also reached agreement on container yard project with many other cities in its ambition to become one of the major container shipping ports of the world.


Why are the two cities a bay apart not joining each other in their bridge and deep sea port project? The situation should be understood in the context of rapid economic growth and inter-city competition. The Chinese have always described themselves as "A plate of scattered sand grains" that would never join or unite with each other. Consider some of the following tales of province and city level economic growth in today's explosive Chinese economy.

The Tale of Three Kingdoms, Modern Version

The economic miracle of the reformed, opened-up China has fueled the growth of three prominent centers of economic activity situated around Hangzhou Bay and the Yangze River Delta: Southern Jiangsu, Northern Zhejiang, and Shanghai.


Southern Jiangsu. Situated on both the north and south banks of the mighty Yanze River as it makes its way to the sea, Jiangsu has carved out a niche as a center for goods and transportation for the 350 million people who live along the river. For the last decade, Jiangsu has sought ways to deepen its river lane to accommodate larger container lines and freighters. Among the key cities of the southern part of Jiangsu province are Suzhou (GDP $25.2 million), Wuxi (GDP $19.4 million), and Nanjing (GDP $15.7 billion). (Jiangsu has had on the drawing board for many years a long bridge linking its city of Nantong to Shanghai).


Northern Zhejiang. Economic growth is also apparent in Zhejiang province, where five cities accounted for over $10 billion in GDP in 2002: Hangzhou, Ningbo, Wenzhou, Shaoxing, and Taizhou. The cities, which are often referred to as the "Five Little Dragons" of Zhejiang, are reimiscent of the aspiring Asian dragons of the late 80's.


Shanghai. Shanghai's estimated year 2002 GDP was $65.5 billion - the highest in the country and more than 80 % higher than Beijing or Guangzhou (which ranked second and third). Shanghai hosts the regional headquarters of more than 300 Fortune 500 firms, in most cases including head administrative offices and financial management centres. However, it is out of those Shanghai regional headquarters that far-flung production facilities spread from Shanghai to Southern Jiangsu and Northern Zhejiangand into the very heartland of China are managed. No wonder Shanghai is now enjoying an international reputation as a dynamic, modern city and an excellent site for foreign investment!


"The Tale of the Three Kingdoms" tells of heroes rising from everywhere like the breaking surf and waves. Modern China has more than its share of municipal heroes, if not exactly rising from everywhere then certainly playing an increasingly important economic role.


The chain of cities from Kunshan to Suzhou, Wuxi, and Nanjing on the southern bank of Yangze River has been blessed with a combination of relatively easy access to the deepest heartland of China, plentiful and high quality human resources, favorable treatment by local governments, and proximity to Shanghai. Foreign investors have taken note, as in the case of Kunshan, a city under the Suzhou city administration, which appears to have one of the highest concentration of Taiwanese factories and firms.


Zhejiang Province. Another rising hero is Zhejiang province, which has a disproportionate number of businesspeople and entrepreneurs. In many cases, they are using innovative marketing strategies such as the "rurals surrounding the cities" cited in my previous Dragon column. More than half of China's leading brands of shirts, men and ladies' apparels are made in Zhejiang. Zhejiang leads all Chinese provinces in the production of motorcycles and washing machines.


Ningbo: Proud Past and Affluent Present. Many prominent and successful businessmen in Hong Kong and Shanghai trace their roots to Ningbo, a city whose 7000 years of cultural history predates the history of China itself by two millennia. Ningbo is now an economic leader, with the highest per capita volume of housing purchases in China. Ningbo's economic muscle is reflected in the way it handled its city government city redevelopment plan in 2001. In most Chinese cities, the city government buys up sufficient new housing units to give to families whose residences would have been reclaimed for the city's redevelopment plan. Ningbo, however, was forced to postpone some of its redevelopment projects because the city government had bought up so many properties there were not enough left to relocate residences in the targeted areas.


Da Yang Shan Island. Dayang Shan (The Big Ocean Mountain) and Xiaoyang Shan (The Small Ocean Mountain) are little more than two small rocks peaking above ocean level, hardly enough to be called "islands." They are located 27 km off the coast of Lucaogang town on the northern coast of Hangzhou Bay, under the administration of Shanghai city. However, Dayang Shan itself is under the administration of Zhejiang province, along with the achipelagoes at the mouth of Hangzhou Bay in East China Sea. While Shanghai's port authority had good reasons for choosing this location seven years ago when the idea of building Shanghai's own deep sea port began, problems have already surfaced. The island's sites for deep sea ports only have a depth of 15 metres, enough to accommodate only the fifth and sixth generation container liners. However, the sea lane depth of only 12 m will certainly limit access of larger ships. Unlike Beilun, which has the large Daxie Island to shield it from the wind, Dayang Shan will have to brave the weather by itself, right in the middle of the Bay of Hangzhou.


While Shanghai grabbed the containers from the throat of Beilun in Yi-u, the provincial government of Zhejiang (with strong support from wealthy Ningbo businessmen) has moved forward to build up the high speed highways linking Hangzhou with Nanjing, Wuxi and Suzhou. For these cities, Beilun port, with the new bridge much nearer and faster than the alternative of going to Dayang Shan Island via the East China Sea Bridge, represents an attractive alternative.


As the construction of the two bridges proceeds, the true color of these two little dragons will continue to be unveiled before the eyes of 1.3 billion Chinese and the international business community.


It has been noted by some astronauts that, looking down at the earth from orbit, the only significant manmade construction visible is the Great Wall of China, a massive structure that snakes along for thousands of kilometers. In the future, perhaps, the two bridges will be a new sight from outer space.


While the Great Wall was built to keep the enemies of Chinese people out of the country, in reality it never really served such a purpose for China. Socially, however, the Great Wall still segregates "insiders" from "outsiders" among Chinese. The two new bridges may be seen in much the same way. They are being constructed - in theory - to link people together and contribute to economic integration. However, it appears that are actually built to exclude certain groups and to wall off the competition, consistent with the old Chinese saying: "Let not your fertile water flow into others' land."


The key question will be whether, as projected, the two bridges and their corresponding ports will really handle over 10 million containers per year, making them among the world's busiest container sea ports. Both Shanghai and Ningbo will certainly need a lot of container transportation businesses from others' land.


Chang Hong is a housing estate built by Chinese government exclusively for foreigners in the early 1990s. However, upon completion, it was found to be below acceptable standards; the estates were then marketed and sold to Chinese residents, mostly working in the field of education and science. "Chang Hong" consists of a block approximately 300-400 meters long separating the Shanghai Teachers Training University and a big cluster of schools, a market, and kindergartens. The thousands of families of the University faculty and staff grew accustomed to sending their children to school and shopping for daily food from the market.


However, the SARS scare (April-June 2002) led to policy changes, with all of the estates locking up their north gate facing the university for most of the day in order to reduce traffic and thus the possible of spread of the dread disease. During the same period, the university locked up its gate to maintain the separation between students and faculty and outsiders. After China was given a clean bill from SARS, however, the gates of Chang Hong estate remained locked, with guards on duty and a notice denying non-residents access. This policy has caused great inconvenience for students and parents, who must make a detour of more than half a kilometer to access the school clusters and the market. The property management company of Chang Hong hired lawyers to defend its decision.


Recently, I passed through the gate of the university (as I usually do, taking advantage of my appearance that can easily be taken as a "foreign teacher"), I noticed a board written in a rather crude handwriting (apparently from some angry detour-ers):


"University village is a private property, No Chang Hong residents or their dogs are allowed to enter."


The sign disappeared after a week.


Just as I was finishing this article, on the bus, I sat in the back watching a middle age lady and her grandson board the crowded bus with its onrushing crowd trying to squeeze in ahead of one another (see ** for a description of how people virtually tackle one another on public buses). In this particular instance, the old lady was not quite quick or nimble enough, and lost out in the squeezing match for the few available seats. Instead of being irritated at the crowd or the rude people who had out-elbowed hi grandmother, the young boy shouted in protest to his grey-haired grandma: "YOU let other get ahead of you again! Why let them get ahead of you again?"


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