Tuesday, July 31, 2012
Romney Merged Law and Business at Harvard
Monday, July 30, 2012
Obama Camp Pushes Romney to Disclose Finances
Dalia Sussman contributed reporting.
Sidebar: An Unexpected Alliance in a Same-Sex Marriage Case
Sunday, July 29, 2012
In Framing Touchy Election Issues, Party Leaders Take Risks
Saturday, July 28, 2012
Democrats Want F.E.C. to Restrict Donor-Shielding Groups
Friday, July 27, 2012
Indictment and Reward Revealed Over Operation Fast and Furious
Genetic Gamble: Genetic Test Changes Game in Cancer Prognosis
And there, Ms. Caton, mother of a 2-year-old daughter, wife of a chicken factory worker, got almost incomprehensibly bad news. The growth was cancer, a melanoma, and it was so huge it filled her eyeball.
“Am I going to die?” Ms. Caton asked. “Is my baby going to have a mommy in five years?”
It is a question that plagues cancer patients. Doctors try to give survival odds based on a tumor’s appearance and size, but often that is just an educated guess.
But Ms. Caton had a new option, something that became possible only in this new genetic age. She could have a genetic test of her tumor that could reveal her prognosis with uncanny precision. The test identifies one of two gene patterns in eye melanomas. Almost everyone in Class 1 — roughly half of patients — is cured when the tumor is removed. As for those in Class 2, 70 to 80 percent will die within five years. Their cancers will re-emerge as growths in the liver. For them, there is no cure and no way to slow the disease.
No test has ever been so accurate in predicting cancer outcomes, researchers said.
The data from studies of the test are “unbelievably impressive,” said Dr. Michael Birrer, an ovarian cancer specialist at Massachusetts General Hospital. “I would die to have something like that in ovarian cancer.”
While for now the ocular melanoma test is in a class by itself, cancer researchers say it is a taste of what may be coming as they continue to investigate the genes of cancer cells. Similar tests, not always as definitive but nonetheless able to give prognostic information, are under development or starting to be used for other cancers, like cancers of the blood.
Having a prognosis allows people to plan their lives, but most do not want to know if they have a gene for an incurable, fatal illness, like Huntington’s disease or early onset Alzheimer’s.
The eye test raises a similar choice, with an added twist. This is not a test offered to healthy people, but to patients who have just gotten the news that they have cancer. The results will either give them reassurance that they will survive the cancer — or near certainty that they will die from it.
Can patients in the throes of getting this terrifying news really make an informed choice about whether they want the test? Are they able to understand at such a fraught time that, for now at least, there is nothing that can save them if they get the bad prognosis?
Some doctors do not offer the test, reasoning that there is little to be gained.
But other doctors, including J. William Harbour of Washington University, who developed the test (but does not profit from its use), encourage patients to have it. And probably because of the way he describes it, Dr. Harbour says his patients almost always want it.
Ms. Caton was no exception. Without the test, doctors would have had to guess her outcome based on the size of her tumor. And the conventional wisdom is that people with growths as large as hers have a slim chance of surviving. But perhaps, her doctors hoped, the genetic test would come up with a different answer.
Heralding the Future
Dr. Harbour, a genial and burly man with salt-and-pepper hair, has a way about him that relaxes patients, makes them feel everything will be O.K.
“I give them as much information as I think they can handle,” Dr. Harbour says.
And he’s an optimist. The ocular melanoma test is just the beginning, he believes, of a new understanding of that cancer — and perhaps other cancers as well — and why they spread.
About 2,000 people a year, or about 5 percent of melanoma patients, have ocular melanoma, a tumor of the dark brown melanocytes that form a sheet much like a photographer’s backdrop behind the retina. Those with very large tumors are most likely to have a bad prognosis, but patients with small tumors also can have the deadly type.
Often there are no symptoms; the tumor may be discovered by an ophthalmologist during a routine exam. Other patients, though, lose vision or see flashing lights or a sea of floaters in an eye, all signs of damage to the retina as the tumor encroaches.
Most get radiation, a highly radioactive disc placed on the surface of the eye that destroys the tumor in a few days and then is taken out. But those with huge tumors, like Ms. Caton, must have their eye removed.
Ocular melanoma specialists had long noticed that some patients did well and the rest did not, but Dr. Harbour wanted to know why.
Thursday, July 26, 2012
Tulelake Journal: Japanese-American Pilgrimage to Internment Camp — Tulelake Journal
Of the 10 internment camps in which about 120,000 Japanese-Americans were confined during the war, it was Tule Lake that held those branded “disloyal,” the ones who answered “no” to two critical questions in a loyalty test administered by the federal government.
After the end of the war, the no-noes, as they were known, not only struggled to find a place in mainstream society, but also were regarded with suspicion by other Japanese-Americans, whose pledge of undivided loyalty and search for larger acceptance could have been threatened by the no-noes.
For decades, the no-noes themselves never explained what lay behind their answers. Most, in fact, never spoke about Tule Lake at all.
“I came here because I want to know why my parents told me never to talk about Tule Lake,” said James Katsumi Nehira, 68, who was riding a bus on a tour here with his daughter, Cherilyn, 37. “They were ostracized and ashamed they were in Tule Lake. I never talked about it. I honored my dad’s wishes until he passed away.”
But in recent years, former detainees have begun speaking during the pilgrimages about why they, or more likely their parents, chose not to answer “yes.” Their stories, as they have filtered out of this small circle into the wider Japanese-American community, have added layers of complexity to the long-held view of the no-noes as simply disloyal troublemakers.
In early 1943, about a year after Japanese-Americans were rounded up into the camps, the American authorities, seeking Japanese language speakers in the military, distributed a loyalty questionnaire to all adults. Question No. 27 asked draft-age men whether they were willing to serve in the armed forces. No. 28 asked whether detainees would “swear unqualified allegiance to the United States” and “forswear any form of allegiance or obedience to the Japanese emperor, or any other foreign government.”
Anything except a simple “yes” to the two questions meant relocation to Tule Lake, which became the most heavily guarded of the camps. Army tanks were stationed here, reinforcing the security provided by 28 guard towers and a seven-foot-high barbed wire fence.
Osamu Hasegawa, 90, recalled that his parents answered “no” after a heated family debate. Because his parents were born in Japan — Japanese immigrants were not allowed to become American citizens until 1952 because of discriminatory immigration laws — they feared that forswearing allegiance to the country of their birth would render them stateless while Mr. Hasegawa and his American-born siblings remained in the United States.
After his parents answered “no,” Mr. Hasegawa became one of the nearly 6,000 Japanese-Americans at Tule Lake to renounce their American citizenship.
“They wanted to go back to Japan to keep the family together,” Mr. Hasegawa said.
Most of the family went to Japan. But his older brother Hiroshi, who had tried to persuade his parents to answer “yes,” remained, eventually joining the 442nd Regimental Combat Team, the Army’s famed Japanese-American unit.
Like most who went to Japan, Mr. Hasegawa and his family regained their citizenship, and they returned to the United States after 11 years. But relations between the brothers remained strained for decades.
“They reconciled only two years ago at the last pilgrimage here,” said Carol Hasegawa, the daughter of Hiroshi, who died shortly after the reconciliation.
Wednesday, July 25, 2012
Obama Trails Romney Again in Battle for Campaign Cash
Tuesday, July 24, 2012
Drilling for Natural Gas Under Cemeteries Raises Concerns
Cell Carriers See Rise in Requests to Aid Surveillance
Monday, July 23, 2012
Wisconsin Nude Beach Draws opposition
Sunday, July 22, 2012
Phoenix Journal: Tortilla Factory Offers a Satisfying Parade, in Corn and Flour
House Panel Appointed in Ethics Inquiry Into Nevada Lawmaker
Saturday, July 21, 2012
The Choice Blog: Counselor's Calendar | July Checklist for Seniors
In March, The Choice introduced a series called Counselor’s Calendar, to keep students on track as they wrangle with the admissions process.
This installment focuses on the class of 2013, who will submit their college applications in a few months. (Rising juniors, your work is just beginning. We published your July checklist on Monday.) We’ve asked Ann E. Selvitelli, the director of college counseling at
Suffield Academy in Suffield, Conn., for some advice on what the members of the class of 2013 should be doing as they prepare for college. — Daniel E. Slotnik
Rising seniors, here is your college admissions checklist:
SENIORS…yes, Class of 2013, your time has come! You are now officially seniors and are readying yourselves for your final year of high school. Along with the excitement of being the academic, athletic, and social leaders of your school comes a nervousness incited by unanswered questions: “Where should I apply to college? Where will I be a year from now? Do I even want to go to college?” Take a deep breath, trust yourself, and ask for help! Here are some tips to get you started this month:
Talk to Your Parents (Really)
I find one of the biggest stressors throughout the college search is communication between the student and his or her parents. Ironically, the ones who love you the most and brought you into this world are very often the same ones who make you want to run away and never discuss college again.
Try designating one day of the week when talking about college is fair game. On that day you and your parents set aside some time to answer each others’ questions and have frank discourse on how your college search is going. Perhaps you leave the “meeting” with to-do lists for each of you. Mom, you will register me for the September ACT and October SAT. Son, you promise to research three colleges your parents would like you to consider closer to home. You get the idea. Parents will relax because the college search is underway, and seniors can rest assured that they will not be peppered with college questions every waking moment. It’s a win-win.
One last note: if you and your parents haven’t talked about how college tuition will be paid, this needs to be an immediate and honest conversation ASAP. If you need help figuring out what you can afford, see finaid.org and thecollegesolution.com.
Summer Reading (and I Don’t Mean Facebook)
Most high schools have a required summer reading list over the summer. I know this because my school does — heck, even my rising kindergartener has one! Here’s the upside: reading can naturally improve your test scores, so make sure you not only do your assigned reading but also read other things of interest to you. If holding a paperback is not your favorite thing, try downloading a summer read onto your iPad or e-reader of choice. And since I know you won’t be ditching your Facebook accounts any time soon, here’s another quick tip for you: it’s time to give your profile a fresh look. A good rule of thumb is that any picture or posting you wouldn’t be comfortable showing to your grandparents (or an admissions officer reading your application) should be taken down. Remember, college admissions officers are savvy and social media is a fun and effective means for them to check you out. Check those privacy settings as well.
Your “Un”-Common Application
The Common Application will open their 2012-2013 online application on August 1, 2012, but there is a paper version available for download now. The application is accepted by over 450 colleges and universities, so there is a pretty good chance you will be using it at least once. If not, it still asks for the same information collected on other applications. Print out a paper copy and start collecting information for the biographical sections. Trust me, you do not want to wake up your parents on November 1st at 11:45 p.m. to ask them what year they graduated from college or what they actually do for a living.
In an ideal world you don’t want to be filling out any part of your college applications at the last minute. Give yourself the gift of time for the fall by getting as much done as possible this summer. Every year, seniors lament frittering away their summertime instead of using it to get a head start. Starting early also gives you time to start working on your college essay. There is the main “personal statement,” but also be on the lookout for those sneaky essays that creep onto a “Supplemental Form” required by some colleges. Anything you can do to be organized before the first school bell rings this fall is a tremendous gift to yourself. You are worth it!
Take Charge
Ever feel like your life is running on autopilot? Do your parents suggest questions to ask on college tours and create outlines of possible essays while you glumly acquiesce? Or are you just so nervous about this whole process that you feel like you are standing in glue, daunted by the college choices in front of you?
Remember this: you are the one going to college. It needs to be a college that fits you. One where you can study what you want, how you want, with the types of people you enjoy and where you can pursue activities you already love and discover others that you will. Jump into the driver’s seat today! It is okay to have co-pilots; in fact, you should. Your parents and guidance or college counselor are there for you, as are your friends. But again, this is about you. Form your own opinions, do your research, ask questions that are important and ignore those that seem rote. Don’t judge one college based on one tour guide or your mother’s friend’s boyfriend’s opinion on a college he knew someone attended in 1991. This is your journey. Get out a pencil and start your own road map.
How far ahead are you on your applications? How responsible have you been in your college search? Let us know in the comment box below.
Friday, July 20, 2012
Grueling Course for Marine Officers Will Open Its Doors to Women
Bits Blog: No 'Death Spiral' for RIM, Chief Executive Says
OTTAWA — The share price of Research In Motion is down by about 95 percent, and the company posted a $512 million quarterly loss last week before announcing a delay in a new phone on which it has staked its future. But in a radio interview on Tuesday morning, Thorsten Heins, the chief executive of the BlackBerry maker, said “there’s nothing wrong with the company as it exists right now.”
After last week’s announcement of the worse-than-expected financial results and the delay of the new BlackBerry 10 line to 2013, several analysts questioned RIM’s ability to stay in business. But during the interview, with the Canadian Broadcasting Corporation, Mr. Heins rejected that analysis as well as suggestions that his optimistic outlook is disconnected from reality.
“This company is not ignoring the world out there nor is it in a death spiral,” he said. “Yes, it is very, very challenged at the moment, specifically in the U.S. market.” He added, “The way I would describe it: This company is really in the middle of a transition. We know what we’re doing; we’re executing on our programs.”
Mr. Heins also announced last week that RIM would lay off about 5,000 of its 16,500 employees. While he said the layoffs would have no impact on the introduction of BlackBerry 10 — a phone and operating system that RIM hoped would again make it an effective competitor in the smartphone market — there were widespread concerns that employees involved in that project would view RIM as a lost cause and start looking for work elsewhere.
This is the second major delay in the introduction of BlackBerry 10. The announcement contradicted earlier, unqualified assertions from Mr. Heins that production of the new phones was on schedule and that they would be released on time.
In the radio interview, Mr. Heins, a former Siemens executive who ran RIM’s handset business until January, blamed the delay on the sheer volume of software that must be processed by RIM’s development group — the same reason he stated in the announcement last week. But he offered no explanation for why that burden was not apparent earlier this year.
“Software development is always a huge task,” he said.
Thursday, July 19, 2012
Palo Alto High School Club Fosters Would-Be Tech Moguls
Wednesday, July 18, 2012
DealBook: Yahoo and Facebook Settle Patent Lawsuits
Yahoo and Facebook agreed on Friday to settle a legal fight over their patent holdings, ending what was shaping up to be one of the nastier court battles in Silicon Valley in recent memory.
Under the terms of the pact, the two companies will expand an existing partnership, including a deeper integration of Facebook’s tools into Yahoo’s content pages.
The two companies have also agreed to cross-license all their patent holdings, which would keep either side from suing the other over intellectual property issues in the future, a person close to one of the companies said.
What the agreement does not include is any sort of cash payout by Facebook, a win for the company.
The pact is intended to heal a rift between two companies that less than a year ago had begun an extensive collaboration. As part of the agreement, Yahoo and Facebook have agreed to work together to promote big events, hoping to draw increased advertising revenue.
“We are looking forward to building on the success we have already seen to provide innovative new products and experiences for both consumers and sponsors,” Ross B. Levinsohn, Yahoo’s interim chief executive, said in a statement. “Combining the premium content and reach of Yahoo as the world’s leading digital media company with Facebook provides branded advertisers with unmatched opportunity.”
Patents have increasingly become a focal point as companies like Apple and Eastman Kodak have turned to suing rivals over intellectual property claims. But such moves are often frowned upon within Silicon Valley. Yahoo took many by surprise earlier this year when it threatened to sue Facebook, claiming that it had violated some of its oldest Web technologies. Yahoo filed suit in March, citing 10 patents in particular.
Several technology commentators criticized Yahoo as a “patent troll” that was simply seeking a big payday.
Analysts also expressed surprise, given that Yahoo’s use of Facebook tools appeared to have improved its own business. Integrating Facebook’s news activity feature into Yahoo pages, for instance, tripled Yahoo’s traffic from Facebook between September and December of 2011.
At the time, Yahoo argued that it was simply trying to protect its intellectual property.
Facebook countersued in April, claiming that Yahoo had breached some of its own patents, some of which the company had purchased.
Yahoo’s original legal campaign was masterminded by Scott Thompson, then the company’s chief executive. The lawsuit was filed at a particularly delicate time for Facebook: about two months before the company was set to go public.
In 2003, Yahoo acquired Overture, a search advertising technology company that had sued Google over patent issues. Yahoo settled the fight the next year, collecting 2.7 million shares from Google before the search giant went public.
But Facebook was prepared to wage a long and costly fight to protect itself against Yahoo’s lawsuit, people close to the company have said.
Settlement talks began shortly after the resignation of Mr. Thompson in May, following the revelation that his academic credentials had been misstated. Soon after becoming interim chief executive, Mr. Levinsohn contacted Sheryl Sandberg, Facebook’s chief operating officer, to begin negotiating a truce, according to people briefed on the matter.
Among Mr. Levinsohn’s concerns was that the patent fight was a distraction from the company’s focus on turning itself around, these people said.
The two sides spent several weeks working on the outlines of a potential agreement, including at the sidelines of the AllThingsD conference in May, these people said.
On Friday, Yahoo’s board — including directors who previously supported the company’s lawsuit — unanimously approved the settlement, one of the people briefed on the matter said.
“I’m pleased that we were able to resolve this in a positive manner and look forward to partnering closely with Ross and the leadership at Yahoo,” Ms. Sandberg said in a statement.
“Together, we can provide users with engaging social experiences while creating value for marketers.”
Shares of Yahoo dipped slightly on Friday, to $15.78, while those of Facebook rose nearly 1 percent, to $31.73.
Tuesday, July 17, 2012
Critic's Notebook: Less Flailing, More Precision: The Joy of Joysticks
Stephen Totilo is the editor in chief of the gaming Web site Kotaku.